On Sunday 26 May 2019, a variety of training courses are offered prior to the opening of the meeting.
Course registration is open to members and guests. Note that you do not need to register for the full meeting to attend a training course.
Continuous professional development.
Up-to-date courses thought by experts in the field.
Unique composition of instructors from all SETAC sectors (business, government and academia).
Well done! Relevant and current content. All speakers strong in experince and all presentations well prepared.
Thank you for the very nice course! Especially useful were the case-studies, to get some “practical” experience.
The course as really great in general, learned a lot! I liked the case study game in the afternoon session.
Very clear and patiently presented, very good pace. Obvious depth of knowledge from presenters.
Excellent course and should be held more often and more widely for scientists of all fields, highly recommended.
Congratulations! Very intersting training course! Maybe more information about risk assessment.
Superb course, delivered by real experts in area presenting the latest techniques. “R skills” are necessary.
Sunday, 26 May | 8:15 – 17:00
THIS COURSE IS SOLD OUT.
This course will start at 9:30.
The European regulation REACH entered into force in 2007 to improve the safe use of chemicals. Under REACH, industry has to prepare registration dossiers containing, among others, hazard information on their substances. REACH encourages the use of animal tests as last resort and offers the possibility for industry to fulfil the information requirements by using adaptations to standard testing, such as (Q)SAR. These can be used only when the reliability of their outcome is duly justified, ensuring the achievement of a high level of protection of human health and the environment.
Part of the REACH dossiers that industry submits is evaluated for compliance by ECHA. With this process, ECHA confirms that the information requirement listed in REACH are adequately covered in the registration dossier of the substance. Along the years, ECHA has built a solid expertise in the regulatory assessment of the reliability of (Q)SAR models and their predictions.
With this course, ECHA aims at promoting the correct use of (Q)SARs by spreading its expertise to eco-toxicologists, who might be involved in the development of (Q)SAR models or in their regulatory use.
The course is intended for participants with different background (academia, consultants, industry, other regulators), with a basic understanding of ecotoxicology. No prior knowledge of (Q)SAR modelling is required.View the course outline and learning objectives
This course is sold out.
As recently emphasised by EFSA, toxicokinetic-toxicodynamic (TKTD) models are of particular interest for regulatory risk assessment of pesticides for aquatic organisms. TKTD models can encompass a large set of mechanisms describing the compound kinetics inside organisms as well as their effects at the individual level. Compared to classical dose–response models, TKTD approaches have many advantages: accounting for temporal aspects of exposure and toxicity, considering data points all along the experiments and not only at the end, and making predictions for untested situations such as realistic field exposure scenarios (e.g., time-variable pulsed exposure profiles).
The General Unified Threshold model of Survival (GUTS) is within the most recent and innovative TKTD framework to deal with survival toxicity test data but is still underused. This training course aims at presenting the theory of GUTS models and at introducing the participants with dedicated tools allowing the practical use of GUTS models. The course material will be a mixture of lectures and hands-on case studies with ecotoxicological data from recent publications.
This course is sold out!
The open source statistical environment R is an extremely powerful and versatile statistical environment. In recent years there has been an amazing development in terms of added capabilities and extra functionality, making it the preferred data analytic toolbox of many statisticians and researchers in many applied sciences. Moreover, it encourages collaborative and reproducible research. RStudio has dramatically changed how R may interface with other languages and systems such as HTML and MS Word.
Currently, many advanced or recent statistical and visualisation approaches and techniques are implemented much more generally or even only available in R. This is, in particular, true when it comes to statistical approaches used in ecotoxicology, e.g., dose-response analysis.
In this course, the primary focus will be on giving the participants practical experience with using R for analysing ecotoxicological data. Relevant recent statistical methodological advances and concepts will be touched upon. The course material will be a mixture of lectures and hands-on case studies with toxicological data, from recent publications. Participants are encouraged to bring their own data.
Specifically, analysis of variance and linear regression will be briefly revisited before introducing nonlinear regression and more general dose-response analysis, logistic and Poisson regression models, and linear, logistic and nonlinear mixed-effects models. More advanced concepts such as sandwich variance estimators, single-step multiplicity adjustment, benchmark dose estimation, and species sensitivity distributions will also be discussed. Two expert teachers will provide guidance and assistance throughout the course.
The course is intended for PhD students, researchers, and scientists in ecotoxicology and environmental sciences. An elementary understanding of statistical concepts is a prerequisite.View the course outline and learning objectives.
Instructors: Mark Miles (Bayer), Jacoba Wassenberg (Ctgb), Edward Pilling (Dow AgroSciences), Ivo Roessink (WUR Alterra), Nicole Hanewald (BASF), Marco Candolfi (Eurofins), Silvio Knaebe (Eurofins)
Room: Session Room 203B
Regulatory texts on Plant Protection Products (pesticides) require an assessment of the impact of these products on the pollinating species and these texts have been recently updated in Europe and North America in order to take into account the most recent scientific input. In the meantime, expert groups are active in updating the set of testing methods to be used in a revised regulatory context.
This course aims at guiding risk assessors as well as scientists through the updated set of methods and more particularly:
- Providing elements of bee biology as a basis for understanding testing methods set-up, advantages and limitations;
- Providing state of the art of actual testing methods and their developments, linked to OECD, ICP-PR and EPPO activities;
- Discussing the derivation of endpoints that allow a reliable description of products ecotoxicological profile to bees for use in robust risk assessments;
- Role of the testing methods in context of the bigger challenges underlying the protection of pollinators.
In response to concerns that certain environmental chemicals might interfere with the endocrine system of humans and wildlife, regulations have been promulgated in regulatory bodies around the world targeting the evaluation of these types of effects. The purpose of this short-course is to address key topics related to endocrine system evaluation and regulatory requirements around the world. The course provides basic information on vertebrate endocrine systems, mechanisms of control, and adverse effects. The focus is the estrogen, androgen, and thyroid systems, although new endocrine system targets will be discussed. The requirements of the US EPA’s Endocrine Disruptor Screening Program, as well as those for REACH and other regulatory initiatives around the world, including the development of definitions and criteria in the EU, will be reviewed. Screens and tests used in these programmes are presented, including plans for the evolution of the US EPA program, with the use of high throughput in vitro assays, in silico modelling, and development of adverse outcome pathways. Use of weight of evidence evaluations in interpreting the data will be covered. Finally, an interactive simulation will be staged where small groups of participants can engage in a transparent and quantitative weight of evidence evaluation of data.View the course outline and learning objectives.
The definition of the risk assessment given by the OECD Glossary of statistical terms reads: “Risk assessment (of pollution) refers to the quantitative and qualitative evaluation of the risk posed to human health and/or the environment by the actual or potential presence of and exposure to particular pollutants.” REACH and biocides regulations define the necessary steps of the risk assessment.
First step is hazard assessment, and aims to identify all hazards of the substance. For environmental risk assessment under REACH, the determination of relevant environmental classification and of (predicted) non-effect concentrations (PNECs) for each of protection targets should be carried out.
The second step is risk characterisation, including exposure assessment. It shall cover all stages of the chemical substance’s life cycle and any exposures that may relate to its identified hazards.
Chemical managers use the results of risk characterisation for identifying the risk management measures to control the risks posed by these chemicals.
With this course, ECHA aims to create an understanding of the regulatory needs for good quality scientific data on hazards and exposure of chemicals to enable regulatory risk assessment and management of these chemicals. All of this to ensure protection of the human health and environment.
The course is intended for participants with different background (academia, consultants, industry, and other regulators), with a basic or no understanding of ecotoxicology, chemicals testing, risk assessment etc.View the course outline and learning objectives
Sunday, 26 May | 8:15 – 12:15 or 13:00 – 17:00
Instructors: Nathalie Vallotton (Dow Europe GmbH) and Marion Junghans (Swiss Center for Applied Ecotoxicology Eawag-EPFL)
Room: Meeting Room 218
With current analytical methods, it is not uncommon to detect more than 50 substances in a single surface water sample. This course intends to explore the series of tools available to risk assessors when evaluating the potential risks from combined exposures. The course will start with a refresher of the basic terminology and concepts of mixture toxicology and expand to discuss approaches used in the screening assessment of mixtures, such as the toxic unit approach and the summation of risk quotients based on benchmark concentrations (i.e environmental quality standards). The course will expand on tools used for the prioritisation of mixtures including: risk assessment decision tree (IPCS/WHO and CEFIC-MIAT) and the Maximum Cumulative Ratio (MCR). Refinement options for cases where screening approaches are not suitable to alleviate concern will also be introduced. Case studies will highlight how to best focus refinement steps and discuss risk management options. The course will end with a hands-on exercise by the participants to experience and discuss challenges encountered in the handling of co-exposure datasets, options for refinement, results interpretation and decision-making.View the course outline and learning objectives
This course is sold out!
Instructors: Jon Arnot (ARC Arnot Research & Consulting, ARC), Li Li (University of Toronto Scarborough, UTSC), Mark Bonnell (Environment and Climate Change Canada, ECCC) and Liisa Toose (Liisa Toose Environmental Research, LTER)
Room: Meeting Room 218
Thousands of chemicals are undergoing regulatory evaluation for potential hazards and risks to humans and the environment. Data gaps and uncertainties in exposure estimation sometimes limit the application of risk-based methods for chemical assessment. Mechanistic process-based fate and exposure models have been developed for decades and there have been significant advancements in exposure science and exposure models in recent years. This training course will provide introductory background information on fundamental principles of mechanistic, mass balance models including combinations of indoor and outdoor environmental fate and bioaccumulation (toxicokinetics) process. Combined, the models exemplify the capacity for aggregate and cumulative exposure assessment for ecological and human health.
Participants will have hands on experience with parameterising and applying models that can be used to estimate exposures of commercial chemicals to humans and ecological receptors. Case examples will include applications of exposure models for: (i) high-throughput prioritisation when chemical information is limited (i.e., chemical emission data are quite uncertain) and (ii) higher tiered screening-level assessments when some monitoring data are available and/or better information on chemical use and release is available. The latter application will demonstrate inverse modelling techniques for addressing uncertainty in chemical use (emissions). This course is an introductory course, aimed at researchers, registrants and evaluators interested in exposure science for chemical evaluation / assessment.View the course outline and learning objectives
Instructors: Marlene Ågerstrand (ACES, Stockholm University, Sweden), Charmaine Ajao (ECHA, Finland), Allen Burton (Michigan University, USA), Peter Dohmen (BASF SE, Germany) and Glenn Suter (US EPA, USA)
Room: Meeting Room 210
Every day thousands of peer-reviewed articles are published in scientific journals. Unfortunately, not all of them provide reliable, relevant and reproducible information, therefore not really contributing significantly to scientific and regulatory progresses. There is definitely certain pressure in academia to publish, particularly on young scientists. In order to reach a wider audience and to have scientific and/or societal impact (and with positive impact on the authors’ reputation), studies need to be performed in line with ‘good’ science, e.g. robust study design, appropriate statistics, correct data analysis with statements supported by data, and transparent, structured and correct reporting of the experiment.
This course intends to provide guidance on how to conduct and report reliable, relevant and reproducible environmental studies, including unbiased data collection, analysis, and interpretation. Thereby making studies appropriate for use by different stakeholders within research and regulation.
We welcome in particular Master students, PhD students and young scientists; reviewers and editors may also find interesting practical information supporting their functions.View the course outline and learning objectives
|Half-day course||Full-day course|
|Student member||95.00 €||125.00€|
|Non-student member||135.00 €||180.00€|
The course registration fee includes attendance for the course, course materials and coffee break. Full-day courses also include lunch and a second coffee break.
Please note: We have to charge an administrative fee of 40€ for participants ONLY attending a training course and not the full meeting. We cordially invite you to the Welcome Reception on Sunday evening.
- You can add a training course during your meeting registration. Click here.
- You can register for a training course only via the SETAC Europe store.
- Already registered for the meeting and you would like to add a training course to your registration? No problem, simply go to the SETAC Europe store and register for the course of your choice.
Would you have any questions on training courses, please contact SETAC.